Lower serum creatinine is a new risk factor of type 2 diabetes: the Kansai healthcare study.
Harita N, Hayashi T, Sato KK, Nakamura Y, Yoneda T, Endo G, Kambe H.
Diabetes Care. 2009 Mar;32(3):424-6. Epub 2008 Dec 15.
PMID: 19074997
DOI: 10.2337/dc08-1265
An association of serum vitamin D concentrations < 40 nmol/L with acute respiratory tract infection in young Finnish men.
Laaksi I, Ruohola JP, Tuohimaa P, Auvinen A, Haataja R, Pihlajamäki H, Ylikomi T.
Am J Clin Nutr. 2007 Sep;86(3):714-7.
PMID: 17823437
In the July 2005 FASEB Journal, Adrian F. Gombart of the University of California, Los Angeles (UCLA) and his colleagues reported that vitamin D boosts production in white blood cells of one of the antimicrobial compounds that defends the body against germs.\n\nImmediately, Cannell says, the proverbial lightbulb went on in his head: Maybe the high doses of vitamin D that he had been prescribing to virtually all the men on his ward had boosted their natural arsenal of the antimicrobial, called cathelicidin, and protected them from flu. Cannell had been administering the vitamin D because his patients, like many other people in the industrial world, had shown a deficiency:
According to a recent study in the Archives of Internal Medicine, 75 percent of Americans do not get enough Vitamin D. Researchers have found that the deficiency may negatively impact immune function and cardiovascular health and increase cancer risk. Now, a University of Missouri nutritional sciences researcher has found that vitamin D deficiency is associated with inflammation, a negative response of the immune system, in healthy women.
Serum tumor necrosis factor-alpha concentrations are negatively correlated with serum 25(OH)D concentrations in healthy women.
Peterson CA, Heffernan ME.
J Inflamm (Lond). 2008 Jul 24;5:10.
PMID: 18652680
doi:10.1186/1476-9255-5-10
Conclusion
Serum 25(OH)D status is inversely related to TNF-α concentrations in healthy women, which may in part explain this vitamin's role in the prevention and treatment of inflammatory diseases. Results gleaned from this investigation also support the need to re-examine the biological basis for determining optimal vitamin D status.